Radiotherapy for Garrod’s pads (knuckle pads)

Radiotherapy is effective in 89% of patients with Garrod's pads(Garrod's pads are also called dorsal Dupuytren's nodules or knuckle pads)I've been treating Garrod's pads with radiotherapy for many years and found it to be effective in around 70% of people.The article below by Amanda Stark and her co-authors is the first publication reflecting something that …

Radiotherapy is effective in 89% of patients with Garrod’s pads

(Garrod’s pads are also called dorsal Dupuytren’s nodules or knuckle pads)

I’ve been treating Garrod’s pads with radiotherapy for many years and found it to be effective in around 70% of people.

The article below by Amanda Stark and her co-authors is the first publication reflecting something that we are doing routinely

I guess it’s not a great shock that it would be effective, as Garrod’s pads are basically Dupuytren’s/Ledderhose on the knuckles, and we know that radiotherapy is effective at reducing Ledderhose lumps in a recent randomised sham-controlled trial .

But it’s always nice to see real world practice reflected in the literature

Personally I use a very slightly different scheme of treatment:
– 15Gy in 5#
– Review at 3 months
– Consider a further 15Gy in 5#
That way, some patients will only need one phase of treatment rather than the full two phases.

Also, it’s clear that steroid injections are generally not helpful.
And surgery seems to negatively affect the joint.

So radiotherapy seems like a good new standard treatment

Reference:

Stark A, Sharifzadeh Y, Kahn J, et al. (June 11, 2025) Radiotherapy for Symptomatic Knuckle Pads Associated With Dupuytren’s Disease: A Report of a Case Series. Cureus 17(6): e85796. doi:10.7759/cureus.85796

Radiotherapy for Garrod’s pads (knuckle pads)
Radiotherapy for Garrod’s pads (knuckle pads)